Acyl Halides
Medchemexpress LLC N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine | 64325-78-6 | 98.0% | 657.71 | 1 ML
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine serves as an intermediate in various chemical processes. It is intended for research use only and is not sold to patients.
- Used as a chemical intermediate.
- High purity of 98.0%.
- Available in different forms including solid and a 10 mM solution in DMSO.
- Detailed solubility information and stock solution preparation guidance provided.
- Comprehensive documentation including Data Sheet, COA, SDS, and Handling Instructions.
AdipoGen 3-ITCEt-BPO-pyridinium bromide
Chemical. CAS 155863-02-8. Formula C20H18BrN3O2S. MW 444.34. Synthetic. Class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Relatively low extinction coefficient Epsilon∼ >20,000 in EtOH.
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 100mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 50mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
Medchemexpress LLC 4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone | 4551-69-3 | 99.9% | 278.31 | 1 G
4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone is a heterocyclic compound featuring a five-membered ring structure. It serves as a versatile compound in scientific research.
- Can be used as a starting material for organic synthesis.
- Functions as a reagent for organic transformation.
- Acts as a biological probe for studying biological processes.
- Utilized as a biomaterial or organic compound for life sciences research.
AdipoGen 10-Octadecylacridine orange Br
Chemical. CAS 75168-16-0. Formula C35H56BrN3. MW 598.74. Synthetic. Fluorescent reagent with high selectivity. Potential sensitive dye PSD to monitor differences in cell potential as they occur during ion transport through the cell membrane.
Medchemexpress LLC KRN2 bromide | 1390654-28-0 | 98.8% | 524.38 | 1 ML
KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It is for research use only and not sold to patients.
- Selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6.
- Dose-dependently inhibits the NF-κB p65 binding to Nfat5 promoter 1.
- Directly blocks the interaction between NF-κB p65 and its DNA binding sequence.
- Effectively suppresses AIA and CIA in mice.
- Decreases the production of pro-inflammatory cytokines and autoantibodies.
- Reduces macrophage infiltration.
Medchemexpress LLC Thonzonium bromide | 553-08-2 | 99.86% | 1 ML
Thonzonium bromide is an antibacterial agent and monocationic surface-active agent that inhibits RANKL-induced osteoclast formation and bone resorption in vitro. It prevents LPS-induced bone loss in vivo by blocking RANKL-induced activation of NF-κB, ERK, c-Fos, and NFATc1, which are crucial for osteoclast formation. Additionally, it disrupts F-actin ring formation in mature osteoclasts and inhibits proton transport in a dose-dependent manner.
- Inhibits RANKL-induced osteoclast formation
- Prevents LPS-induced bone loss in vivo
- Blocks key signaling pathways for osteoclast formation
- Disrupts F-actin ring formation in mature osteoclasts
- Inhibits proton transport
![Medchemexpress LLC 1-Hexadecanaminium, N-[2-[[(4-methoxyphenyl)methyl]-2-pyrimidinylamino]ethyl]-N,N-dimethyl-, bromide (1:1) | 553-08-2 | 99.9% | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000412988-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1-Hexadecanaminium, N-[2-[[(4-methoxyphenyl)methyl]-2-pyrimidinylamino]ethyl]-N,N-dimethyl-, bromide (1:1) | 553-08-2 | 99.9% | 100 MG
Thonzonium bromide is an antibacterial agent and a monocationic surface-active agent. It inhibits RANKL-induced osteoclast formation and bone resorption in vitro, and prevents LPS-induced bone loss in vivo. This compound also inhibits proton transport in a dose-dependent manner (EC50=69 μM).
- Antibacterial agent.
- Monocationic surface-active agent.
- Inhibits RANKL-induced osteoclast formation and bone resorption in vitro.
- Prevents LPS-induced bone loss in vivo.
- Inhibits proton transport in a dose-dependent manner (EC50=69 μM).
- Blocks RANKL-induced activation of NF-κB, ERK, and c-Fos, as well as NFATc1 induction.
- Disrupts F-actin ring formation, causing disturbances in cytoskeletal structure in mature osteoclasts during bone resorption.
- Exhibits protective effects in an in vivo murine model of LPS-induced calvarial osteolysis.
AdipoGen 4-ITCB-MPO-pyridinium bromide
Chemical. CAS 155862-90-1. Formula C23H18BrN3O2S. MW 480.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Major disadvantage rel. low extinction coefficient.
Medchemexpress LLC Thonzonium bromide | 553-08-2 | 99.7% | 50 MG
Thonzonium bromide is an antibacterial and monocationic surface-active agent. It inhibits proton transport and has been shown to inhibit RANKL-induced osteoclast formation and bone resorption in vitro. This compound also prevents LPS-induced bone loss in vivo.
- Inhibits proton transport
- Prevents LPS-induced bone loss
- Blocks activation of NF-κB, ERK, and c-Fos
- Disrupts F-actin ring formation in mature osteoclasts
- Exhibits protective effects in murine models
TARGETMOL CHEMICALS INC Tarloxotinib bromide 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Tarloxotinib bromide (TH-4000) is an irreversible inhibitor of EGFR/HER2. Purity 97.15%
Cayman Chemical p-Benzoyl-L-phenylalnIn 1g
A photoreactive derivative of L-phenylalanine; can be incorporated into synthetic peptides and used as a photolabel to identify the residues involved in peptide-protein interactions; has been incorporated into GPCRs to identify potential ligand binding sites
Medchemexpress LLC Aclidinium (Bromide) | 320345-99-1 | C26H30BrNO4S2 | 100 MG
Aclidinium (Bromide) | 320345-99-1 | C26H30BrNO4S2 | 100 MG